MedicineComputer vision

Bioptimus H-optimus

Pathology foundation models from France's Bioptimus with 1.1B parameters, plus the compact H0-mini. The first version is open under Apache 2.0. Does not replace a doctor; decisions are made by a specialist.

Developer
Bioptimus, France
First release
Jul 2024
Latest release
Feb 2025
Sizes
86M (H0-mini) – 1,1B
License
Commercial use with conditionsMixed: H-optimus-0 — Apache 2.0, H-optimus-1 and H0-mini — CC-BY-NC-ND 4.0 (commercial use under a separate license)
Running
On your own serverNeeds a GPU
Industries
Healthcare, Science and research
Deploy on your server Hugging Face GitHub

What it does

  • Histology slide patch features for research models
  • A prototype for sorting slides by tissue type
  • Research projects linking morphology and molecular data

Where it is used

Clinic research departmentsPharma and biotech R&D

Hardware requirements

LaptopLaptop or regular PC, up to 8 GB of VRAM — smaller versions
fits
1 GPUOne GPU with 16–80 GB — mid-size versions
fits
ClusterServer with several GPUs — flagship versions
no versions

Versions

  1. H0-mini
  2. H-optimus-1
  3. H-optimus-0

How to run it

On your own serverWeights are downloaded from Hugging Face and served with vLLM (load and API) or llama.cpp (modest hardware). The model then runs in a closed network with no per-request fees.Hugging Face
How much hardware you needCalculate the VRAM for the model size, context length and number of concurrent requests.Open the hardware calculator

I can set this up end to end: pick the model size, deploy it on your server and connect it to your systems.

Frequently asked questions

Can Bioptimus H-optimus be used in a commercial project?

With conditions. License: Mixed: H-optimus-0 — Apache 2.0, H-optimus-1 and H0-mini — CC-BY-NC-ND 4.0 (commercial use under a separate license). Restrictions vary — region, company revenue, attribution requirements. Have a lawyer check the terms before a commercial launch.

What hardware does Bioptimus H-optimus need?

At minimum: Laptop or regular PC, up to 8 GB of VRAM — smaller versions. Without a GPU the model is not practical. You can calculate the exact VRAM for your model size and context in the hardware calculator.

Does Bioptimus H-optimus support Russian?

Language does not matter for this model: it does not work with text.

Where can I download Bioptimus H-optimus and what does it cost?

The Bioptimus H-optimus weights are open and free to download. You only pay for the hardware it runs on and for the setup. Source links are at the bottom of this page.

How I deploy it for clients

  1. SelectionI pick the model size for your task and hardware and test it on your examples.
  2. DeploymentI deploy it on your server or in a closed network and provide an API.
  3. Fine-tuningI fine-tune it on your data (LoRA) or connect a knowledge base — whichever is cheaper for the task.
  4. IntegrationI connect it to your CRM, ERP, bot, website or team chat and set up monitoring.

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Details

Source: huggingface.co/api/models?author=bioptimus. Data checked against the model card on 22 Sep 2026. Have a lawyer review the license before commercial launch.