Open-source medical AI models

Medical models help analyze images, clinical notes and discharge summaries and answer questions over clinical materials. They support doctors and clinic staff and do not replace a diagnosis. Always check the license, terms for medical use, data protection requirements and whether the model can be deployed on-premises.

22 open model families in this collection.Updated 22 Sep 2026Open the full catalog with filters
Medicine2026

Carbon-X

Hugging Face (HuggingFaceBio) · USA

An open 14.8B language model for working with DNA, built on Qwen3-14B. You send a raw sequence right in an ordinary chat, and it answers in English: it judges whether a mutation is benign or pathogenic, finds regions that control gene activity, assigns a sequence to an organism group, predicts the next bases and explains its reasoning. DNA and text go in one stream, with DNA encoded in groups of six bases. By the authors' tests, on five sets it scores 66.7% without reasoning, 27 points above Qwen3-14B, and costs about 1,800 times less than GPT-6.1 Sol at a close result. It fits on a single 80 GB card, so sensitive data can stay with you. Viral data was excluded from training because of the risks. The conclusions are computed and do not replace laboratory verification.

  • assessing DNA variants: benign or pathogenic
  • finding regions that control gene activity
  • a research assistant for biologists on your own server
Sizes
14.8B
Hardware
from: 1 GPU
Commercial use allowedDetails
Medicine2026

NV-Reason-CT

NVIDIA · USA

A language model for computed tomography: looks at a whole chest or abdominal CT volume, not separate slices, writes structured reports and answers questions with reasoning. English only.

  • a draft CT report for a physician
  • yes-or-no answers about a scan with reasoning
  • research in medical imaging
Sizes
4B (based on Qwen3.5-4B with a 3D encoder)
Hardware
from: 1 GPU
Commercial use allowedDetails
Medicine2026

FleXray

MIT CSAIL, Massachusetts General Hospital and Harvard Medical School · USA

Finds 60 anatomical structures on an X-ray: ribs, vertebrae, pelvis and limb bones. They can be used to measure, for example, the curvature angle of the spine automatically. It does not look for pathologies and does not tell right from left.

  • labeling anatomy on X-ray images
  • measuring the spine curvature angle
  • matching fluoroscopy frames with CT for navigation
Sizes
a small U-Net, 256 by 256 pixel images
Hardware
from: Laptop
Non-commercial onlyDetails
MedicineGGUF2023–2026

HuatuoGPT

FreedomIntelligence (The Chinese University of Hong Kong, Shenzhen) · China

A large family of medical models: chat, an imaging version, the reasoning HuatuoGPT-o1 and the new HuatuoGPT-3 on Qwen3. Does not replace a doctor; decisions are made by a specialist.

  • Draft discharge summaries for a doctor to review
  • Searching medical literature
  • Hints for doctors when reviewing images (Vision)
Sizes
7B – 72B
Hardware
from: Laptop
Commercial use allowedDetails
MedicineOllama2023–2026

Meditron

EPFL · Switzerland

Open medical models from Swiss EPFL, fine-tuned on clinical guidelines on top of various base models. Does not replace a doctor; decisions are made by a specialist.

  • Answering staff questions based on clinical guidelines
  • Draft discharge summaries for a doctor to review
  • Searching medical literature
Sizes
2B – 70B
Hardware
from: Laptop
Commercial use with conditionsDetails
MedicineGGUF2025–2026

Hulu-Med

Zhejiang University · China

A medical model for text, images, 3D scans and video: from a light 4B to a large MoE. Does not replace a doctor; decisions are made by a specialist.

  • Hints for doctors when reviewing images and CT scans
  • Draft reports and discharge summaries
  • Searching medical literature
Sizes
4B – 235B-A22B
Hardware
from: Laptop
Commercial use allowedDetails
MedicineGGUF2025–2026

AntAngelMed

Ant Healthcare (Ant Group) and Zhejiang Provincial Medical Information Center · China

A large medical MoE model based on Ling-flash-2.0: 100B parameters with 6B active, so it answers quickly. Does not replace a doctor; decisions are made by a specialist.

  • Reference answers to staff on clinical questions
  • Draft discharge summaries for a doctor to review
  • Searching medical literature
Sizes
100B-A6B
Hardware
from: 1 GPU
Commercial use allowedDetails
Medicine2023–2026

CheXagent / CheXOne

Stanford AIMI · USA

Stanford models for chest X-rays: they describe the image and prepare a draft report. Does not replace a doctor; decisions are made by a specialist.

  • A draft X-ray description for the radiologist
  • Hints for doctors when reviewing images
  • Checking reports for completeness
Sizes
3B – 8B
Hardware
from: Laptop
Commercial use with conditionsDetails
MedicineGGUF2025–2026

Lingshu

Alibaba DAMO Academy · China

Alibaba's medical model based on Qwen2.5-VL: understands many types of medical images and medical text, and can reason step by step. Does not replace a doctor; decisions are made by a specialist.

  • Hints for doctors when reviewing images
  • Draft reports and discharge summaries
  • Searching medical literature
Sizes
7B – 32B
Hardware
from: Laptop
Commercial use allowedDetails
MedicineOllama2025–2026

MedGemma

Google · USA

Google's medical version of Gemma: reads medical texts and images (X-ray, dermatology, histology). A tool for doctors and developers; does not replace a doctor, decisions are made by a specialist.

  • Draft discharge summaries and reports for a doctor to review
  • Hints for doctors when reviewing images
  • Searching and summarising medical literature
Sizes
4B – 27B
Hardware
from: Laptop
Commercial use with conditionsDetails
MedicineGGUF2025

II-Medical

Intelligent Internet · UK

Reasoning medical models on Qwen3, designed to run on an ordinary computer. Does not replace a doctor; decisions are made by a specialist.

  • Reference answers to staff with the reasoning shown
  • Draft discharge summaries for a doctor to review
  • Searching medical literature
Sizes
7B – 32B
Hardware
from: Laptop
Commercial use allowedDetails
Medicine2025

MedSigLIP

Google · USA

Google's lightweight encoder for medical images and text, the same one inside MedGemma. Sorts images and finds similar ones. Does not replace a doctor; decisions are made by a specialist.

  • Finding similar images in a clinic's archive
  • Pre-sorting images for a doctor
  • A base for your own image classifiers
Sizes
about 0.9B
Hardware
from: Laptop
Commercial use with conditionsDetails
Acoustic monitoring2024–2025

HeAR

Google · USA

A model for health sounds: coughing, breathing, throat clearing. It provides features on top of which a researcher builds their own model and draws no conclusions about illness itself. It does not replace a doctor; decisions are made by a specialist. Voice recordings are personal data, so check the procedure with a lawyer.

  • Features of cough and breathing sounds for your own model
  • Research projects in health acoustics
  • Selecting cough and breathing fragments from a recording
Sizes
a ViT-Large class model, trained on more than 300 million two-second clips
Hardware
from: Laptop
Commercial use with conditionsDetails
Medicine2024–2025

Bioptimus H-optimus

Bioptimus · France

Pathology foundation models from France's Bioptimus with 1.1B parameters, plus the compact H0-mini. The first version is open under Apache 2.0. Does not replace a doctor; decisions are made by a specialist.

  • Histology slide patch features for research models
  • A prototype for sorting slides by tissue type
  • Research projects linking morphology and molecular data
Sizes
86M (H0-mini) – 1,1B
Hardware
from: Laptop
Commercial use with conditionsDetails
Medicine2024–2025

MahmoodLab UNI / UNI 2

Mahmood Lab (Mass General Brigham, Harvard) · USA

A foundation model for histology slides: turns patches of digital slides into features for tissue classification. Does not replace a doctor; decisions are made by a specialist.

  • Research classifiers of tissue types from digital slides
  • Finding similar cases in a slide archive
  • Preparing features for research prognosis models
Sizes
about 300M (UNI) – about 680M (UNI2-h)
Hardware
from: Laptop
Non-commercial onlyDetails
Medicine2024

MahmoodLab CONCH / TITAN

Mahmood Lab (Mass General Brigham, Harvard) · USA

Image-plus-text models for pathology: search slides by an English description, classify without fine-tuning; TITAN describes a whole slide. Does not replace a doctor; decisions are made by a specialist.

  • Text-query search across a slide archive for research
  • Draft slide descriptions for research projects
  • Tissue classification without labels at the start of a study
Sizes
about 160M – 300M
Hardware
from: Laptop
Non-commercial onlyDetails
MedicineNot maintained2024

Paige Virchow

Paige · USA

Paige's pathology foundation model, trained on millions of digital slides. The first version is Apache 2.0, the second is for research only. Does not replace a doctor; decisions are made by a specialist.

  • Slide patch features for research classifiers
  • Selecting slides for re-review in research projects
  • Comparison with other pathology models on your own archive
Sizes
about 632M
Hardware
from: Laptop
Commercial use with conditionsDetails
MedicineGGUFNot maintained2023–2024

Med42

M42 Health · UAE

Clinical models from Abu Dhabi-based M42, built on Llama and tuned to answer medical questions. Does not replace a doctor; decisions are made by a specialist.

  • Reference answers to staff on clinical questions
  • Draft discharge summaries and letters for a doctor to review
  • Searching medical literature
Sizes
8B – 70B
Hardware
from: Laptop
Commercial use with conditionsDetails
MedicineGGUFNot maintained2024

BioMistral

Avignon University and Nantes University · France

Mistral 7B fine-tuned on PubMed Central papers, plus several merges with the general model. Compact and easy to run. Does not replace a doctor; decisions are made by a specialist.

  • Searching and summarising medical papers
  • Draft reference materials for staff
  • Explaining medical terminology
Sizes
7B
Hardware
from: Laptop
Commercial use allowedDetails
MedicineGGUFNot maintained2024

OpenBioLLM

Saama AI Research · India

Llama 3 fine-tuned on medical and biological data. One of the first strong open medical models of 2024. Does not replace a doctor; decisions are made by a specialist.

  • Extracting data from medical documents
  • Draft discharge summaries for a doctor to review
  • Searching medical literature
Sizes
8B, 70B
Hardware
from: Laptop
Commercial use with conditionsDetails
MedicineNot maintained2023

Clinical Camel

Bo Wang's lab (University of Toronto, Vector Institute) · Canada

An early medical model on Llama 2 70B, trained on dialogues based on medical texts. Now mainly of research interest. Does not replace a doctor; decisions are made by a specialist.

  • Research pilots on medical dialogue
  • Training materials for staff
  • Comparison with newer medical models
Sizes
70B
Hardware
from: 1 GPU
Non-commercial onlyDetails
MedicineNot maintained2023

RadFM

Shanghai Jiao Tong University and Shanghai AI Lab · China

An early general-purpose radiology model: understands 2D and 3D images (CT, MRI) together with text. More of a research base. Does not replace a doctor; decisions are made by a specialist.

  • Research pilots on CT and MRI analysis
  • Hints for doctors when reviewing images
  • A base for fine-tuning on the clinic's own images
Sizes
size not stated on the model card
Hardware
from: 1 GPU
Commercial use with conditionsDetails

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